Six public APIs, no keys and no paywall. Queries are scoped to title and abstract rather than full text, because a full-text hit on Curcuma in a reference list is not evidence of anything. Everything retrieved is then passed through an interaction-vocabulary gate: a paper is admitted only if it actually describes an interaction, not merely because it names a plant and a drug in the same abstract. What survives is ranked against an eight-level evidence hierarchy, so a randomised trial outranks a review that cites it.
Additive dopaminergic blockade, QT prolongation and sedation, plus CYP1A2, 2D6 and 3A4 modulation of clozapine, risperidone and quetiapine exposure.
Expected clinically: Extrapyramidal symptoms, QT prolongation, excess sedation, or loss of antipsychotic control with inducers.