Six public APIs, no keys and no paywall. Queries are scoped to title and abstract rather than full text, because a full-text hit on Curcuma in a reference list is not evidence of anything. Everything retrieved is then passed through an interaction-vocabulary gate: a paper is admitted only if it actually describes an interaction, not merely because it names a plant and a drug in the same abstract. What survives is ranked against an eight-level evidence hierarchy, so a randomised trial outranks a review that cites it.
Botanical CNS depressants prolong anaesthetic recovery, antiplatelet and coumarin constituents raise surgical bleeding, and sympathomimetics destabilise intraoperative haemodynamics. CYP modulation changes opioid and muscle-relaxant handling.
Expected clinically: Prolonged emergence, intraoperative haemodynamic instability, excess surgical bleeding, delayed neuraxial haematoma.