PhytoNexus

PhytoNexus

Department of Pharmacognosy · Herb-Drug Interaction Intelligence Platform · generated 27 Jul 2026 01:59 IST
Poaceae · source entry 32

Cymbopogon citratus

Lemongrass

Tier 2 · Verified 1 curated · 0 predicted 2Moderate Risk index 33.2
Interaction profile

01 Identity and provenance

Accepted binomial
Cymbopogon citratus
Common names
Lemongrass
Family (APG IV)
Poaceae
Part used
Leaf
Verification tier
Tier 2 · Verified Clinical columns reviewed and a source is on record.
Reviewer note (2026 audit)
Reference not supplied - claim unverified against primary literature.

02 Constituent chemistry

Chemical classMarker compoundSynthetic analogue in use
Citral , Myrcene Citral , Germinal
Leaf
Chlorhexidine

The analogue column is what makes the interaction reasoning tractable: where a constituent has a marketed structural counterpart, the counterpart's interaction profile is the starting hypothesis for the plant.

Looking up structures and physicochemical properties from PubChem…

03 Stated application

Reported activity
Antimicrobial
Marketed in
Lemon grass oil
Reported adverse effects
Skin irritation

04 Interaction matrix

Source column, verbatim: Hypersensitive
Normalised onto 1 canonical drug class below.

Curated from the reviewed source

Drug classSeverityMechanism type ProvenanceExpected effect
Hypersensitivity and allergy risk
Immunology
2Moderate Immunological curated B Urticaria, angio-oedema, allergic contact dermatitis, anaphylaxis; cross-… why ▾

05 Hazard register

The audit recorded no hazard beyond the interaction profile. The controlled-vocabulary field reads not assessed, which means the assessment has not been done rather than that it came back clear.

06 Confusable material

These entries could be mistaken for this one in trade, in the herbarium, or in a prescription. Powdered material is often indistinguishable, so the check is macroscopic, microscopic and chromatographic rather than nominal.

Cymbopogon winterianus
Citronella
Poaceae Same genus (Cymbopogon)

07 Mechanism map

Chemistry sorts to the left, pharmacology to the right. Dashed edges are predicted. Drag nodes, scroll to zoom, export at 3× for a figure.

species
chemical class
marker compound
drug class
expected effect
hazard

08 Open literature

Abstract-scoped query built from this binomial, its common names and its marker compounds, run live against Europe PMC, PubMed and OpenAlex, then ranked locally against an evidence hierarchy.

Checking openFDA spontaneous reports…

09 Isomechanistic neighbours

Species whose interaction profile overlaps this one, ranked by shared severity weight rather than by count — a shared contraindication counts for more than a shared minor signal. Practical use: these are the plants you should not stack with this one, because the mechanisms summate.

SpeciesFamilyShared classes WeightJaccard
Artemisia annua
Sweet Wormwood
Asteraceae 1 0.20
Cichorium intybus
Chicory
Asteraceae 1 0.20
Taraxacum officinale
Dandelion
Asteraceae 1 0.20
Tanacetum parthenium
Feverfew
Asteraceae 1 0.20
Inula racemosa
Pushkarmool
Asteraceae 1 0.20
Saussurea costus
Kuth
Asteraceae 1 0.20

10 References and notes

No citation is on record for this entry. That is itself the finding: the audit flagged it, and it is why the entry does not carry an A evidence grade.

Curator notes

No notes yet.

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