PhytoNexus

PhytoNexus

Department of Pharmacognosy · Herb-Drug Interaction Intelligence Platform · generated 27 Jul 2026 02:00 IST
Fabaceae · source entry 94

Pterocarpus santalinus

Red Sandalwood

Tier 2 · Verified 1 curated · 0 predicted 3Major Risk index 49.8
Interaction profile

01 Identity and provenance

Accepted binomial
Pterocarpus santalinus
Common names
Red Sandalwood
Family (APG IV)
Fabaceae
Part used
Heartwood
Verification tier
Tier 2 · Verified Clinical columns reviewed and a source is on record.
Reviewer note (2026 audit)
Reference not supplied - claim unverified against primary literature.

02 Constituent chemistry

Chemical classMarker compoundSynthetic analogue in use
Santalins Pterostilbene
Heartwood
Ibuprofen

The analogue column is what makes the interaction reasoning tractable: where a constituent has a marketed structural counterpart, the counterpart's interaction profile is the starting hypothesis for the plant.

Looking up structures and physicochemical properties from PubChem…

03 Stated application

Reported activity
Antioxidant
Marketed in
Sandal wood poweder
Reported adverse effects
Skin irritation

04 Interaction matrix

Source column, verbatim: Antidiabetic drug
Normalised onto 1 canonical drug class below.

Curated from the reviewed source

Drug classSeverityMechanism type ProvenanceExpected effect
Antidiabetic drugs (insulin, sulfonylureas, biguanides, GLP-1, SGLT2)
Endocrine
3Major PD-additive curated B Symptomatic hypoglycaemia, sweating, tremor, confusion; severe events rep… why ▾

05 Hazard register

The audit recorded no hazard beyond the interaction profile. The controlled-vocabulary field reads not assessed, which means the assessment has not been done rather than that it came back clear.

06 Confusable material

These entries could be mistaken for this one in trade, in the herbarium, or in a prescription. Powdered material is often indistinguishable, so the check is macroscopic, microscopic and chromatographic rather than nominal.

Pterocarpus marsupium
Vijaysar
Fabaceae Same genus (Pterocarpus)
Santalum album
Sandalwood
Santalaceae Shares the common name "sandalwood"

07 Mechanism map

Chemistry sorts to the left, pharmacology to the right. Dashed edges are predicted. Drag nodes, scroll to zoom, export at 3× for a figure.

species
chemical class
marker compound
drug class
expected effect
hazard

08 Open literature

Abstract-scoped query built from this binomial, its common names and its marker compounds, run live against Europe PMC, PubMed and OpenAlex, then ranked locally against an evidence hierarchy.

Checking openFDA spontaneous reports…

09 Isomechanistic neighbours

Species whose interaction profile overlaps this one, ranked by shared severity weight rather than by count — a shared contraindication counts for more than a shared minor signal. Practical use: these are the plants you should not stack with this one, because the mechanisms summate.

SpeciesFamilyShared classes WeightJaccard
Anethum graveolens
Dill
Apiaceae 1 1.00
Andrographis paniculata
Kalmegh
Acanthaceae 1 1.00
Swertia chirayita
Chirata
Gentianaceae 1 0.50
Garcinia cambogia
Garcinia
Clusiaceae 1 1.00
Boswellia serrata
Boswellia
Burseraceae 1 1.00
Rosa canina
Rosehip
Rosaceae 1 0.50

10 References and notes

No citation is on record for this entry. That is itself the finding: the audit flagged it, and it is why the entry does not carry an A evidence grade.

Curator notes

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