01 Identity and provenance
- Accepted binomial
- Boswellia serrata
- Common names
- Boswellia
- Family (APG IV)
- Burseraceae
- Part used
- Gum resin
- Verification tier
- Tier 2 · Verified Clinical columns reviewed and a source is on record.
- Reviewer note (2026 audit)
- DUPLICATE SPECIES - Boswellia serrata also appears as entry 93. Database holds 97 unique species, not 100.
CORRECTED - Chemical composition / class: AKBA and the boswellic acids are triterpenoid acids from the gum resin, not essential-oil constituents. | Active chemical moiety: Abbreviation expanded.
Reference not supplied - claim unverified against primary literature. - Duplicate entries
- This binomial appears more than once in the source workbook. Entry 93 (verified) Both are retained rather than merged so the original numbering stays traceable.
02 Constituent chemistry
| Chemical class | Marker compound | Synthetic analogue in use |
|---|---|---|
| Pentacyclic triterpenoid acids (boswellic acids) | AKBA (3-O-acetyl-11-keto-beta-boswellic acid)
Gum resin
|
Celecoxib |
The analogue column is what makes the interaction reasoning tractable: where a constituent has a marketed structural counterpart, the counterpart's interaction profile is the starting hypothesis for the plant.
03 Stated application
- Reported activity
- Osteoarthritis
- Marketed in
- Boswelia capsules
- Reported adverse effects
- diarrhea
04 Interaction matrix
Source column, verbatim: Antidiabetic drug
Normalised onto 1 canonical drug class below.
Curated from the reviewed source
| Drug class | Severity | Mechanism type | Provenance | Expected effect | |
|---|---|---|---|---|---|
|
Antidiabetic drugs (insulin, sulfonylureas, biguanides, GLP-1, SGLT2)
Endocrine
|
3Major | PD-additive | curated B | Symptomatic hypoglycaemia, sweating, tremor, confusion; severe events rep… | why ▾ |
Class mechanism. Hypoglycaemic botanicals act through insulin secretagogue, insulin-sensitising, alpha-glucosidase-inhibiting or glucose-transport routes. Added to a titrated pharmacological regimen the effects summate rather than plateau.
| |||||
05 Hazard register
The audit recorded no hazard beyond the interaction profile. The controlled-vocabulary field reads not assessed, which means the assessment has not been done rather than that it came back clear.
06 Confusable material
These entries could be mistaken for this one in trade, in the herbarium, or in a prescription. Powdered material is often indistinguishable, so the check is macroscopic, microscopic and chromatographic rather than nominal.
| Boswellia sacra
Frankincense |
Burseraceae | Same genus (Boswellia) |
| Boswellia serrata
Salai Guggul |
Burseraceae | Same genus (Boswellia) |
07 Mechanism map
Chemistry sorts to the left, pharmacology to the right. Dashed edges are predicted. Drag nodes, scroll to zoom, export at 3× for a figure.
08 Open literature
Abstract-scoped query built from this binomial, its common names and its marker compounds, run live against Europe PMC, PubMed and OpenAlex, then ranked locally against an evidence hierarchy.
09 Isomechanistic neighbours
Species whose interaction profile overlaps this one, ranked by shared severity weight rather than by count — a shared contraindication counts for more than a shared minor signal. Practical use: these are the plants you should not stack with this one, because the mechanisms summate.
| Species | Family | Shared classes | Weight | Jaccard |
|---|---|---|---|---|
| Anethum graveolens
Dill |
Apiaceae | 1 | 1.00 | |
| Andrographis paniculata
Kalmegh |
Acanthaceae | 1 | 1.00 | |
| Swertia chirayita
Chirata |
Gentianaceae | 1 | 0.50 | |
| Garcinia cambogia
Garcinia |
Clusiaceae | 1 | 1.00 | |
| Pterocarpus santalinus
Red Sandalwood |
Fabaceae | 1 | 1.00 | |
| Rosa canina
Rosehip |
Rosaceae | 1 | 0.50 |
10 References and notes
No citation is on record for this entry. That is itself the finding: the audit flagged it, and it is why the entry does not carry an A evidence grade.
Curator notes
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